Post-Doctoral position : Research Associate in Biomechanics - In vivo identification of biomechanical properties in arteries

Job description

Mines Saint-Etienne (MSE), one of the graduate schools of Institut Mines Télécom, the #1 group of graduate schools of engineering and management in France under the supervision of the Ministry of the Economy, Industry and Digital Technology, is assigned missions of education, research and innovation, transfer to industry and scientific, technological and industrial culture.

MSE consists of 2,400 graduate and postgraduate students, 400 staff, a consolidated budget of €46M, three sites on the Saint-Etienne campus (Auvergne Rhone-Alpes region, Lyon Saint-Etienne metropolitan area), a campus in Gardanne (SUD region, Aix Marseille metropolitan area), a site in Lyon within the digital campus of Auvergne Rhone-Alpes Region, six research units, five teaching and research centres and one of the leading French science community centres (La Rotonde €1M budget and +40,000 visitors per year). The Times Higher Education World University Ranking ranked us for 2022 in the 251-300 range for Engineering and Technology. Our work environment is characterised by high Faculty-to-Student, Staff-to-Faculty and PhD-to-Faculty ratios, as well as comprehensive state-of-the-art experimental and computational facilities for research, teaching and transfer to industry.

Website: https://www.mines-stetienne.fr/

The CIS brings together 70 people, including 18 professors in engineering industrial/computing, biomechanics and healthcare engineering. Since its creation in 2004, the CIS has been representative of the ability of Mines Saint-Etienne to acquire leadership on innovative themes such as, for example,

Soft tissue biomechanics. SAINBIOSE (INSERM UMR 1059) brings together researchers from the CIS (biomechanics, biomaterials and bioengineering), the faculty of Medicine from Jean Monnet University, Saint-Etienne University Hospital, Inserm and the French Blood Establishment. The global scientific objective of SAINBIOSE is a better understanding and of biostress in osteoarticular (LBTO team) and cardiovascular pathologie (DVH team).

Website: https://sainbiose.univ-st-etienne.fr/

Biomechanics, experimental and computational, is a major research topic of SAINBIOSE, which goes from modelling the mechanical behaviour of tissues to clinical and industrial applications, especially with the textile industry.

Job requirements

1. Missions 

We are planning to open a non-permanent position of research associate to conduct a project of "basic research" consisting in developing and validating a method for in vivo identification of biomechanical properties in arteries. The project is part of a bigger grant, funded by the French national Research Agency, whose aim is to achieve patient specific simulations of stent deployment using the assistance of intravascular OCT (optical coherence tomography).

The research will be carried out at Mines Saint-Etienne, within the SAINBIOSE research unit (Inserm U1059). It is based at the Centre Ingénierie et Santé (Hospital campus at the North of Saint-Etienne). There will be collaboration with and regular visits to hospitals and other laboratories in France.

The project will involve formulating mechanical constitutive models for healthy and pathological arteries, establish the inverse problem and implement the methodology to solve it using the Virtual Fields Method, validate the inverse method using in vitro data and then perform the identification extracted from the training OCT database. Novel approaches of mechanical modelling based on machine learning will be considered. The project will take place in a research group having 15 years experience in arterial biomechanics and mechanobiology (https://emse.fr/~avril/).

2. Profile of the candidate 

The candidate should hold a PhD degree in the field of solid mechanics, fluid mechanics or biomechanics and should satisfy the following criteria:

  • Capacity to manage projects and to successfully integrate a team and a group,
  • Interest for partnership-based research: direct industrial partnerships, collaborative research, support to start-ups …,
  • International experience,
  • Writing skills testified with significant scientific production.


3. Recruitment conditions

  • non-permanent position of research associate
  • duration : a one-year contract renewable 3 times
  • Full time
  • Remuneration according to the rules defined by the Institut Mines Télécom's management framework
  • Desired start date: 1st March 2022.

4. Application procedures

To apply, send by email to avril@emse.fr: a cover letter, a curriculum vitae and recommendation letters. These documents should be received by December 31th, 2022 at the latest on the RECRUITEE platform:

https://institutminestelecom.recruitee.com/o/postdoctoral-position-research-associate-in-biomechanics-in-vivo-identification-of-biomechanical-properties-in-arteries

Candidates selected for an interview will be informed rapidly. Part of the interview will be held in English.

5. For more information

Research contact :

Stephane AVRIL – Researcher

avril@emse.fr

06 03 75 50 29

Administrative contact :

Milica PETKOVIC, human ressources

milica.petkovic@emse.fr

04 77 42 02 08


References:

F Frauziols, J Molimard, L Navarro, P Badel, M Viallon, R Testa, S Avril, Prediction of the Biomechanical Effects of Compression Therapy by Finite Element Modeling and Ultrasound Elastography, IEEE Transactions on Biomedical Engineering, 2015, 62(4), 1011-1019

PY Rohan, P Badel, B Lun, D Rastel, S Avril, Prediction of the biomechanical effects of compression therapy on deep veins using finite element modelling, Annals of biomedical engineering, 2014, 43 (2), 314-324

S. Avril, L. Bouten, L. Dubuis, S. Drapier, JF Pouget. Mixed experimental and numerical approach for characterizing the biomechanical response of the human leg under elastic compression. ASME Journal of Biomechanical Engineering -2010, 132, 031006.


Data protection :

https://www.mines-stetienne.fr/wp-content/uploads/2018/12/Informations-des-candidats-sur-les-traitements-de-donn%C3%A9es-personnelles.pdf