Post-Doctoral position - "Computational modelling of vascular aging conditions"- CDD 18 months
- On-site
- Saint-Etienne, Auvergne-Rhône-Alpes, France
- Ingénierie et services de la santé
Job description
Joining Mines Saint-Étienne means committing to an institution where science and innovation build a more sustainable future. It is a school of excellence where everyone has the opportunity to unlock their full potential and contribute to tackling the challenges of tomorrow.
Ranked among the top engineering schools in France and recognized worldwide, our school, a member of the Institut Mines-Télécom, educates the talents of tomorrow while actively addressing major industrial, digital, and environmental challenges. By joining us, you become part of a community of 500 members of staff, 2,500 students and take part in an ambitious project: combining academic excellence, cutting-edge research, and positive societal impact.
The Institut Mines-Télécom brings together France’s leading Grandes Ecoles to tackle major industrial, digital, energy, and environmental challenges. With its eight public Grandes Écoles and two affiliated Graduate Schools, it is the leading public institute dedicated to engineers and managers. Together, we imagine and build a sustainable future by educating the leaders who will shape tomorrow’s transitions.
🎯 What we expect from you
As post-doc, you will be at the heart of our missions in research and innovation, assigned to the SAINBIOSE lab. SAINBIOSE (INSERM UMR 1059) brings together researchers from Mines Saint-Etienne (biomechanics, biomaterials and bioengineering), the faculty of Medicine from Jean Monnet University, Saint-Etienne University Hospital, Inserm and the French Blood Establishment. The global scientific objective of SAINBIOSE is a better understanding and of biostress in osteoarticular (LBTO team) and cardiovascular pathology (DVH team).
Website: https://sainbiose-lab.fr/
Biomechanics, experimental and computational, is a major research topic of SAINBIOSE, which goes from modelling the mechanical behaviour of tissues to clinical and industrial applications, especially with the textile industry. In 2024, Prof Stéphane Avril was awarded an ERC Advanced grant from the European Research Council for the project JuvenTwin “Multiscale mechanobiological synergies in vascular homeostasis, ageing and rejuvenation”, which aims to establish multiscale digital twins of ageing effects on vascular mechanobiology and to simulate and screen effective rejuvenation treatments. This project will take place in a research group having 15 years experience in biomechanics and mechanobiology (https://emse.fr/~avril/).
We open a non-permanent position of post-doctoral fellow to join the Avril’s team working on JuvenTwin’s project. The work will be carried out at Mines Saint-Etienne, within the SAINBIOSE research unit (Inserm U1059). It is based at the Centre Ingénierie et Santé (Hospital campus at the North of Saint-Etienne).
The objective of the post-doctoral fellow will be to develop an innovative computational models (multi-scale digital twin, machine learning, growth and remodeling) in which we will calculate deformation fields using a combination of traditional finite-element model and physics informed neural network for realistic microstructures of arterial extracellular matrix (reconstructed from patient-specific micro-architectures) in which a large population of prestressed cells will be embedded. Temporal variations of cell prestress in the model will be informed from the patient-specific data of collaborators in the JuvenTwin project and using a computational model of cell signalling networks.
Your ability to work in a project-based environment and to create links between teaching, research, and practical applications will be essential for success.
Job requirements
🔍 What we are looking for
You hold a PhD degree in mechanics/biomechanics
Junior applicants accepted: [yes]
And you have:
Good knowledge of computational methods for mechanics and biomechanics
First experience with developing a computational model
Your additional strengths:
Interest in coding
Multi-scale modelling
Expertise in front-end and back-end development
Capacity to successfully integrate a team and a group within a R&D environment,
🌍 Why join Mines Saint Etienne ?
We support each of our employees on the path to excellence, with the conviction that together, we can have a lasting and significant impact on our world.
Joining Mines Saint-Etienne is the opportunity to find:
• A stimulating environment: Cutting-edge experimental resources, a welcoming working environment and a solid international network (T.I.M.E., EULIST).
• A real impact: Contractual research projects worth €11 million/year, mainly with industrial partners, A science culture centre, La Rotonde, which has been committed to science outreach for 25 years, welcoming over 50,000 visitors per year.
• An incomparable quality of life: 46/49 days of paid leave, partial remote working, 75% reimbursed public transport, financial support for carpooling and cycling and a social barometer where 83% of employees praise the quality of life at work.
Let's build a more sustainable future, through science, engineering, and projects that make sense.
📩 Apply now !
Application deadline: 30/06/2026
🔗 Submit your application to our dedicated platform
As part of its Equality, Diversity, and Inclusion policy, the École des Mines de Saint-Étienne is committed to fair treatment of all applicants.
ℹ️ Additionnal information
Remuneration set according to the candidate's profile, according to the rules defined by the management framework of the Institut Mines Télécom
The positions offered for recruitment are open to all with, on request, facilities for candidates with disabilities
Position open to civil servants (category A and B) and/or people on public contracts
All applications may be subject to an administrative investigation
The selected candidates, after review of their applications, will be invited for interviews online.
📞 Contacts
· For the content of the position:
Stéphane AVRIL - Researcher
Mail : avril@emse.fr
Tel. : 04 77 42 01 88
· For HR and administrative aspects :
Milica PETKOVIC - Gestionnaire RH
Mail : milica.petkovic@mines-stetienne.fr
Tél. : +33 (0)4 77 42 93 05
Liens utiles :
Ecole :
https://www.mines-stetienne.fr/
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